The HOMA Calculator 2.2 version can calculate insulin and sugar levels within a wide range, however there may be some limitations to the accuracy of the HOMA index calculation based on individual factors such as insulin sensitivity and beta cell function. It is best to consult with a healthcare professional for interpretation of HOMA values.
You have to input the values of the fasting patient's plasma glucose along with the values of the plasma RIA insulin. Instead of RIA insulin, values of C-peptide or fasting specific insulin can be used.
Can I use HOMA calculator to assess insulin sensitivity and resistance in Wistar rats in experimental model of type II DM?
D
Answer by
Dan Angel
No, from what it seems, you can't use HOMA calculator to assess insulin sensitivity and resistance of Wistar rats in experimental model of type II DM. The application uses the HOMA2 model to estimate beta cell function (%B) and insulin sensitivity (%S) for an individual from simultaneously measured fasting plasma glucose and fasting plasma RIA insulin values. I recommend that you contact the official developers for further details. You can get in touch with them using +44 (0)1865 857233 phone number or [email protected] email address.
Limitation of homa index if any..?
The HOMA Calculator 2.2 version can calculate insulin and sugar levels within a wide range, however there may be some limitations to the accuracy of the HOMA index calculation based on individual factors such as insulin sensitivity and beta cell function. It is best to consult with a healthcare professional for interpretation of HOMA values.
I wanted to know the formula which you were using in it.
The HOMA Calculator for Windows uses the following formula to calculate the Homeostatic Model Assessment (HOMA) index:
HOMA-IR = (fasting insulin (μU/mL) x fasting glucose (mmol/L)) / 22.5
This formula is commonly used to estimate insulin resistance and beta-cell function.
You have to input the values of the fasting patient's plasma glucose along with the values of the plasma RIA insulin. Instead of RIA insulin, values of C-peptide or fasting specific insulin can be used.
Can I use HOMA calculator to assess insulin sensitivity and resistance in Wistar rats in experimental model of type II DM?
No, from what it seems, you can't use HOMA calculator to assess insulin sensitivity and resistance of Wistar rats in experimental model of type II DM. The application uses the HOMA2 model to estimate beta cell function (%B) and insulin sensitivity (%S) for an individual from simultaneously measured fasting plasma glucose and fasting plasma RIA insulin values. I recommend that you contact the official developers for further details. You can get in touch with them using +44 (0)1865 857233 phone number or [email protected] email address.